Kbckdyq

ARPC3
Strwythurau PDB Orthologau:PDBe RCSB Rhestr o ddynodwyr PDB 2P9N, 1TYQ, 1U2V, 4JD2, 3DXK, 3UKU, 3UKR, 2P9P, 2P9K, 2P9U, 3ULE, 3RSE, 2P9S, 2P9I, 4XF2, 2P9L, 1K8K, 3DXM, 4XEI
Dynodwyr
Cyfenwau	ARPC3, ARC21, p21-Arc, actin related protein 2/3 complex subunit 3
Dynodwyr allanol	OMIM: 604225 MGI: 1928375 HomoloGene: 4178 GeneCards: ARPC3
Lleoliad y genyn (llygoedn) Cr. Cromosom 5 (llygoden)[1] Band 5|5 F Start 122,391,878 bp[1] End 122,414,184 bp[1]
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • actin filament binding • structural constituent of cytoskeleton • protein binding • actin binding Cydrannau o'r gell • cytoplasm • cytosol • cell projection • membrane • focal adhesion • Arp2/3 complex • actin cytoskeleton • extracellular exosome • Cytosgerbwd • lamellipodium • cell leading edge • filamentous actin • growth cone leading edge • cnewyllyn cell • site of double-strand break Prosesau biolegol • movement of cell or subcellular component • Fc-gamma receptor signaling pathway involved in phagocytosis • ephrin receptor signaling pathway • regulation of actin filament polymerization • Arp2/3 complex-mediated actin nucleation • cellular response to nerve growth factor stimulus • membrane organization • actin polymerization-dependent cell motility Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10094	56378
Ensembl	ENSG00000111229	ENSMUSG00000029465
UniProt	O15145	Q9JM76
RefSeq (mRNA)	NM_001287222 NM_001278556	NM_019824
RefSeq (protein)	NP_001265485 NP_001274151	NP_062798
Lleoliad (UCSC)	n/a	Chr : 122.39 – 122.41 Mb
PubMed search	[2]	[3]
Wicidata
Gweld/Golygu Bod dynol Gweld/Golygu Llygoden

Protein sy'n cael ei godio yn y corff dynol gan y genyn ARPC3 yw ARPC3 a elwir hefyd yn Actin related protein 2/3 complex subunit 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q24.11.^[4]

Cyfystyron[golygu | golygu cod y dudalen]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ARPC3.

• ARC21
• p21-Arc

Llyfryddiaeth[golygu | golygu cod y dudalen]

• "Nogo-B regulates migration and contraction of airway smooth muscle cells by decreasing ARPC 2/3 and increasing MYL-9 expression. ". Respir Res. 2011. PMID 21251247.
• "An actin-filament-binding interface on the Arp2/3 complex is critical for nucleation and branch stability. ". Proc Natl Acad Sci U S A. 2010. PMID 20404198.
• "Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases. ". Nat Med. 2016. PMID 27748747.
• "A CpG-SNP Located within the ARPC3 Gene Promoter Is Associated with Hypertriglyceridemia in Severely Obese Patients. ". Ann Nutr Metab. 2016. PMID 27055012.
• "Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes.". Nature. 1997. PMID 9000076.

Cyfeiriadau[golygu | golygu cod y dudalen]